Research Assistant Position Available
Department of biochemistry & biophysics
Weill Cornell Medicine
The lab of Dr. Andres Leschziner at Weill Cornell Medicine seeks a motivated and intellectually curious Research Assistant to join our research team for post-baccalaureate studies. Our lab has a culture of providing excellent post-bac training and placing people in PhD and MD/PhD programs (our two most recent post-bacs joined the PhD program at UCSF and the MD/PhD program at Yale).
The Leschziner lab studies the molecular mechanisms of chromatin dynamics and microtubule-based intracellular transport and are particularly interested in the connection between defects in transport and neurodegenerative diseases. We focus on the molecular machines involved in these processes and use a range of techniques including cryo-electron microscopy (cryo-EM), biochemistry, in vitro reconstitution, and cell-based assays. We collaborate with labs with expertise in cell biology, single-molecule biophysics and cryo-electron tomography. The Leschziner lab is funded by the National Institutes of Health and the LITE initiative (via the Michael J Fox Foundation).
We are seeking a Research Assistant who will commit to two to three years of post-bac training in our lab, in a paid position. The Research Assistant will be mentored by a senior lab member to develop their own research project, as well as perform general lab duties. Ideal candidates will have a BA or BS in the biological or chemical sciences or related field and will have experience in one or more of the following areas: molecular biology methods (cloning, PCR, qPCR, etc.), tissue culture of human and/or insect cells, protein biochemistry (Western blots, protein purification from E. coli, insect cells, and/ or human cells, etc.), computational methods (structural biology, coding, machine learning, etc.).
Interested and qualified candidates should apply here. Interested applicants are also welcome to write directly to Dr. Leschziner (aleschziner@ucsd.edu) and include their CVs.
Postdoctoral Positions Available
Department of biochemistry & biophysics
Weill Cornell Medicine
The Leschziner lab at Weill Cornell Medicine is seeking postdoctoral fellows to join our project on LRRK2 and Parkinson’s Disease. This project is a collaboration with the groups of Samara Reck-Peterson (HHMI / Weill Cornell Medicine), Kevan Shokat (UCSF), and Stefan Knapp (University of Frankfurt). We are using a combination of structural (cryo-EM and cryo-ET), biophysical (single-molecule assays), biochemical and cell biological approaches to understand LRRK2’s role in cells and how malfunction leads to Parkinson’s Disease.
The successful candidate must have a Ph.D. in the biological, physical, or chemical sciences. Preferred candidates will have experience working with complex reconstituted systems using one or more of the following approaches: cryo-EM, X-ray crystallography, biochemistry.
Interested candidates should submit a cover letter and CV to aleschziner@ucsd.edu. In addition, please have three referees send letters of recommendation directly to aleschziner@ucsd.edu. Applications without references will not be considered. Applications will be reviewed starting immediately until the positions are filled.